Vol. 5, Issue 2, Part B (2023)

A lack of physical activity stands out as a modifiable risk factor contributing to the development of depression. Exercise proves effective in alleviating depression symptoms across both clinical and non-clinical populations. Its impact extends to influential systems such as neurotransmitters and functions akin to antidepressants in the brain. Exercise fosters elevated neurotrophin levels while curtailing cortisol release through inhibition of the hypothalamic–pituitary–adrenal axis, resulting in a diminished psychological stress response. The positive outcomes derived from exercise parallel the effects of antidepressants among individuals grappling with depression. In light of these observations, this paper undertakes an analysis of exercise as a viable alternative to antidepressant treatments. The exploration encompasses a review of the depression concept, including its causes, signs, and symptoms. Additionally, the paper delves into the mechanisms and transformative effects of exercise on depression. Multiple studies underscore the merits of exercise for individuals with depression, suggesting that its effects may indeed serve as a plausible alternative to antidepressants in certain scenarios.